Nana Mizuki (水樹 奈々; Mizuki Nana) was born as Nana Kondo on January 21, 1980 in Niihama, Ehime, Japan, and is part of the large contingent of Japanese pop stars who began her career among the ranks of anime voice actors when she voiced a character in the show 時空探偵ゲンシクン (Flint the Time Detective) and a character in the video game Noël: La Neige in 1998.

However, Nana showed interest in singing by the time she was five, singing enka (a form of traditional Japanese music), and released a casette in 1993 called つがざくら(Phyllodoce Nipponica) under her birth name by the time she was 13.

Building her sound on a particularly demure format at the beginning (following her best known characters), Mizuki soon built a following for her slightly harder pop, utilizing a somewhat stronger and deeper voice than was the case with many other female vocalists in the same genre. Releasing her first singles in 2000 and her first full-length album at the end of 2001, Mizuki began with basic pop influences from the anime series that she had worked on.

As her career developed and additional albums were released, she began infusing her sound with rock elements, adding faster riffs to her songs, as well as an occasional electric guitar solo.

The stylistic break from the rest of her cohorts proved a worthwhile course, as Mizuki was pushed to the forefront of the J-Pop genre album by album, culminating in her seventh full-length, Great Activity, which held a Top Ten position on the Oricon charts for nearly a full year after its release in late 2007.

On July 7, 2020, Mizuki announced on her blog post that she had been in a relationship for a while, and that they had married; her husband was also reported to be in the music industry. Then, on November 6, she announced that she was pregnant with their first child

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