Described by St. Vincent as the inner monologue of depression and anxiety, “Big Time Nothing” is the third and final single off her seventh studio album All Born Screaming. It was released on April 23, 2024, three days before the album’s release. Unlike the rest of the record, which was written solely by Annie Clark, the song had a writing contribution from Cate Le Bon, who also provided backing vocals for the album-closing title track.

The lyrics explore the conflict between individuality and conformity to societal norms through clear instructions and contradictory commands, with some music critics taking the second verse and the chorus as a comment on the bad faith and falsity of life online.