“D.R.U.G.S” refers to the acronym coined by Lupe Fiasco, as an abbreviation for “Don’t Ruin Us God Said”. Ab-Soul compared himself to Lupe in 2014: “I’m Lupe Fiasco on drugs”.

On this track, Ab-Soul reflects on his love for those close to him (his father in particular) and the feeling of having the same love for drugs – maybe even moreso than his family. The message is similar to his song “Just Have Fun”:

So, do the drugs, don’t let drugs do you

The single was released with a music video as the fourth single from DWTW, two days before the album’s release. Mac Miller features on the hook for some background vocals.