“4422” is sung entirely by UK singer-songwriter Sampha, and marks his third musical collaboration with Drake, following 2013’s “The Motion” and “Too Much.”

The song’s meaning is sufficiently opaque, but the prevailing theory is that Sampha’s alluding to the UK and Freetown, Sierra Leone—the country code for the UK is “44” and the area code for Freetown is “22.” He was born in the UK, but his family originated in Freetown, and he traveled from the locations in a short film for his February 2017 album Process. He may also be referencing biblical verse Isaiah 44:22, which is about forgiveness.