On “1-800-273-8255,” Logic shows that suicide is never the answer to anyone’s problems. He wants people to know that there is always help available, such as the National Suicide Prevention Lifeline, whose phone number is the title of this song. Although 9-8-8 became the new phone number for the lifeline since 2022, the original phone number still continues to remain available. In fact, the song was released in partnership with the NSPL.

In an interview with Genius, Logic said that this song details the story of someone calling the NSPL wanting to commit suicide but after a conversation with the NSPL representative, the caller soon after decides he wants to live.

Logic teased the song various times on both Twitter and on Instagram stories as well.