“Nothing Breaks Like a Heart” marks the first collaboration between producer Mark Ronson and country-pop star Miley Cyrus. The song speaks of a desperate scene between two lovers and underscores the dour persona surrounding heartbreak against other disasters in life. The track was initially teased by Mark Ronson on Twitter with an unknown artist, which was later revealed to be Miley the following day.

The duo performed their song for the first time on the Graham Norton Show on 7 December 2018.