This angelic dance-floor ballad introduces the third and final act of Chromatica. The track marks the second collaboration between Sir Elton John and Lady Gaga.

On this track, Lady Gaga talks about her songwriting process. She reveals that “Sound” is her God and it is the reason for all her artistic revelations.

The title of the track has been interpreted in several different ways. “Sine” is pronounced like “sign” alluding to a “Sign from above” keeping in the theme of comparing the sound with God. “Sine” has also been interpreted as being a play on the word “sin”.

During an interview with Rolling Stone in May 2020, co-writer Axwell revealed that the song was originally meant to be a collaboration between Elton John and house duo Ryan Tedder from around 2013. He commented:

I had this old song we worked on, like, seven years ago with Elton John. We tried working on it and we couldn’t really get it where we wanted it.