On “Big Slimes,” Chris, Thug and Thug’s YSL labelmates rap about women, guns, and their lavish lifestyles. The track’s instrumental was used in promotional countdown videos leading up to Slime & B’s release.
Executive producer and featured artist Lil Duke originally previewed a version of “Big Slimes” without Chris' vocals on Instagram Live on December 23, 2019.
“Big Slimes,” “She Bumped Her Head,” and “Help Me Breathe” are the only three songs on the mixtape where Thug recorded his verses on separate days from the rest.