“Vaccine” is the second single from Logic in 2021, following “Intro,” but also using a much different sound.

The track name drops Bobby Tarantino III, which would be the latest installment of his trap mixtape series that he started in 2016 and continued in 2018. This single’s release comes one day after the five-year anniversary of Bobby Tarantino.

Logic uses this single, at a time where the COVID-19 vaccine is allowing countries to begin loosening restrictions and open back up, to talk about his return to rap. He includes a note about his son and takes a shot at those who continue to talk down about him.