“2 BEST FRIENDS” sonically sounds like a bright and cute pop song, but with darker lyrics to contrast the joyous sound. Lyrically, Knight deals with the emotions associated with an un-reciprocated feeling towards another person: while he is trying to show interest in a potential lover or partner, they do not seem to be giving him the time of day.

On June 2, 2022, Awsten posted a video to Twitter, captioned with 15 red circles, enough to spell “Two Best Friends”, teasing the song title. In the replies of that tweet, the band account tweeted “2BF”, also representing the title of the song.