The debut single from the Luniz is a song about pooling money together to get more green—in the form of a fat sack of weed. Yukmouth credits Numskull with devising the song’s concept. With its universal theme, the song took off internationally, reaching the Top 10 on the pop charts of numerous countries, including #1 in the Netherlands. In the US, the song peaked at #8 on the Billboard Hot 100 and #4 on the Hot R&B/Hip-Hop Songs chart as the single reached platinum status. Its success was also propelled by the remix version, which features an all-star cast of Bay Area rappers.

The song was produced by Tone Capone, who replayed a sample of Club Nouveau’s 1986 hit “Why You Treat Me So Bad.” However, a claim was made that Club Nouveau’s sampled riff was actually lifted from the 1986 song “Thinkin' About Ya” by the group Timex Social Club, best known for their hit single “Rumors.” The lead vocals for both Timex Social Club songs featured Michael Marshall, the singer on the chorus of “I Got 5 On It.”

Appropriately, Complex ranked “I Got 5 On It” in the #5 spot on their list of The Best Songs About Weed and #1 on their list of The 50 Greatest Bay Area Rap Songs.

The song received more national attention when it was given a horrorcore remix and featured in the movie trailer for Jordan Peele’s 2019 thriller Us.